{"id":171,"date":"2021-11-25T15:43:13","date_gmt":"2021-11-25T06:43:13","guid":{"rendered":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/WordPress\/?p=171"},"modified":"2021-11-25T15:52:29","modified_gmt":"2021-11-25T06:52:29","slug":"catalytic-enantioselective-inverse-electron-demand-hetero%e2%80%90diels-alder-reaction-with-allylsilanes","status":"publish","type":"post","link":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/archives\/171","title":{"rendered":"Catalytic Enantioselective Inverse Electron Demand Hetero\u2010Diels\u2013Alder Reaction with Allylsilanes"},"content":{"rendered":"\n<p>Yuki Matsumura, Takahiro Suzuki, Akira Sakakura,* Kazuaki Ishihara&nbsp;*&nbsp;<br><em>Angew. Chem. Int. Ed.<\/em><strong>2014<\/strong>,&nbsp;<em>53<\/em>&nbsp;(24), 6131\u20136134. &nbsp;(Published online:&nbsp;29&nbsp;Apr 2014)&nbsp;<br><a href=\"https:\/\/doi.org\/10.1002\/anie.201402934\">DOI: 10.1002\/anie.201402934<img decoding=\"async\" src=\"http:\/\/www.cc.okayama-u.ac.jp\/~sakakura\/bioorgchem\/_src\/9485\/img20180629093542651479.png\" alt=\"LinkIcon\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/WordPress\/wp-content\/uploads\/2021\/08\/heteroda.png\" alt=\"\" class=\"wp-image-172\" width=\"480\" height=\"149\" srcset=\"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/WordPress\/wp-content\/uploads\/2021\/08\/heteroda.png 960w, http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/WordPress\/wp-content\/uploads\/2021\/08\/heteroda-300x93.png 300w, http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/WordPress\/wp-content\/uploads\/2021\/08\/heteroda-768x238.png 768w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p><strong>New on the block:<\/strong>&nbsp; The first diastereo\u2010 and enantioselective title reaction of \u03b2,\u03b3\u2010unsaturated \u03b1\u2010ketoesters with allylsilanes is described. Chiral copper(II) catalysts successfully activate the \u03b2,\u03b3\u2010unsaturated \u03b1\u2010ketoesters and promote the reaction with allylsilanes with excellent enantioselectivities. This process represents a new entry to chiral oxanes, which are useful building blocks. Tf=trifluoromethanesulfonyl.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Yuki Matsumura, Takahiro Suzuki, Akira Sakakura,* Kazuaki Ishihara&nbsp;*&nbsp;Angew. Chem. Int. Ed.2014,&#038;nbsp [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":172,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[6],"tags":[],"class_list":["post-171","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"_links":{"self":[{"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/posts\/171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/comments?post=171"}],"version-history":[{"count":2,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/posts\/171\/revisions"}],"predecessor-version":[{"id":248,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/posts\/171\/revisions\/248"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/media\/172"}],"wp:attachment":[{"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/media?parent=171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/categories?post=171"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/achem.okayama-u.ac.jp\/bioorgchem\/wp-json\/wp\/v2\/tags?post=171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}