Indirect Electrochemical Radical Cyclization of Bromo Acetals by the Combined Use of Cobaloxime and Sacrificial Electrode

Inokuchi, T.; Kawafuchi, H.; Aoki, K.; Yoshida, A.; Torii, S. Bull. Chem. Soc. Jpn. 1994, 67, 595.

An improved procedure for the electrochemical radical cyclization of 1-bromo-3-oxa-5-alkynes has been developed by the combined use of (chloropyridine)cobaloxime(III) and a zinc plate as a sacrificial anode in an undivided cell. The reaction is feasible with 5 mol% of the cobalt catalyst and applicable to a variety of bromo acetals under neutral conditions