2-Substituted Penems, New Candidates for Cephalosporinase Inhibitors

Tanaka, H.; Kameyama, Y.; Sumida, S.-i.; Torii, S. Bioorg. Med. Chem. Lett. 1993, 3, 2253.

Upon preliminary bioassay experiments, C(2)-substituted penams 5 exibit promising activities particularly against E. Cloacae(cephalosporinase).