A Facile Conversion of 2-Substituted Acrylamides to 1,3-Disubstituted 3-Bromo-2-Azetidinones

Torii, S.; Okumoto, H.; Yabuki, H. Synth. Commun. 1993, 23, 517.

N-Substituted 2,3-dibromo-2-alkylacrylamides obtained by the bromination of 2-alkylacrylamides were converted to 1,3-disubstituted 3-bromo-2-azetidinones in excellent yields upon treatment with potassium carbonate in acetone under refluxing.