Novel Synthesis of Functionalized Benzo[b]furans and the Homologues by Use of a Palladium-Copper Catalyst System

Torii, S.; Xu, L. H.; Okumoto, H., Synlett 1992, 515.

A facile synthesis of 2-substituted and 2,5-disubstituted benzo[b]furans and homologues 4, by the coupling of 2-hydroxyaryliodides 1 and terminal acetylenes 2 in the presence of bis(triphenylphosphine)palladium(II) chloride and copper(I) iodide as catalysts, has been accomplished.