A Direct Approach to 2-Substituted 1,4-Dihydro-4-oxo-quinoline- 3-Carboxylates by Palladium-Catalyzed Carbonylative Cyclization

Torii, S.; Okumoto, H.; Xu, L. H. Tetrahedron Lett. 1990, 31, 7175.

Carbonylation of 3-substituted 3-(2-haloarylamino)prop-2-enoates in the presence of palladium catalyst under 20 Kgcm² of CO at 120 ｡C resulted in the heterocyclizatio to form a variety of 2-substituted 1,4-dihydro-4-oxo-quinoline-3-carboxylates in good yields.