Carbonylative [2+2] Cycloaddition for the Construction of b-Lactam Skeleton with Palladium Catalyst

Torii, S.; Okumoto, H.; Sadakane, M.; Hai, A. K. M. A.; Tanaka, H. Tetrahedron Lett. 1993, 34, 6553.

Palladium-catalyzed carbonylation of allyl diethyl phosphate in the presence of imines under CO pressure (30 Kgcm^-2) gave highly stereoselectively either cis- or trans-3-vinyl-b-lactam compounds, depending on the nature of the imines employed in high yields.