坂倉 彰 （SAKAKURA Akira）
岡山大学学術研究院環境生命自然科学学域
応用化学専攻 応用化学講座
教授
〒700-8530
岡山市北区津島中3-1-1 工学部6号館361室
TEL&FAX: 086-251-8215
E-mail: sakakura＠okayama-u.ac.jp
ORCID: 0000-0002-2995-1251
ResearcherID: A-6319-2013
学歴
1993年 名古屋大学理学部化学科卒業（山田靜之教授）
1995年 名古屋大学大学院理学研究科化学専攻博士前期課程修了（山田靜之教授）
2000年 名古屋大学大学院人間情報学研究科物質・生命情報学専攻博士後期課程満期退学（早川芳宏教授）
2000年 博士（学術）取得（名古屋大学）
職歴
2000年 名古屋大学大学院環境学研究科 博士研究員（村田静昭教授）
2001年 筑波大学化学系 助手（木越英夫教授）
2003年 名古屋大学大学院工学研究科 講師（石原一彰教授）
2007年 名古屋大学エコトピア科学研究所 准教授（石原一彰教授）
2012年 岡山大学大学院自然科学研究科（工学系） 教授
所属学会
日本化学会，有機合成化学協会，ヨウ素学会，アメリカ化学会
趣味
旅行，読書，模型制作
受賞
1. 有機合成化学協会東海支部奨励賞 (2005年)
「生物活性物質を指向した低環境負荷型触媒的脱水縮合反応の開拓」
2. 有機合成化学協会 萬有製薬研究企画賞 (2006年)
「求核触媒による不斉ハロゲン化を利用した含ハロゲン環状化合物のエナンチオ選択的合成法の開拓」
3. 日本化学会第86春季年会 若い世代の特別講演賞 (2006年)
「生物活性物質合成を指向した環境低負荷脱水縮合反応の開拓」
4. Thieme Chemistry Journal Award (2006年)
the editorial boards of Synlett and Synthesis, Thieme Chemistry in Thieme Publishing Group
5. 有機合成化学奨励賞 (2008年)
「酸・塩基複合塩を鍵とする高機能触媒の設計及び高選択的合成法の開拓」
6. Banyu Chemist Award (2009年)
「酸・塩基複合塩型触媒の精密設計を基盤とした高選択的合成法の開拓」
“Development of Highly Selective Reactions Based on Rational Design of Acid-Base Combined Salt Catalysts”
7. Asian Core Program Lectureship Award (2010年)
“Design of Bronsted Base-Assisted Boronic Acid Catalysis for the Dehydrative Intramolecular Condensation of Dicarboxylic Acids”
The 5th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-5)
発表論文
1. "Synthetic Studies on Aplyronine A, a Potent Antitumor Substance of Marine Origin: Stereocontrolled Synthesis of the C21–C34 Segment"
Hideo Kigoshi, Makoto Ojika, Kiyotake Suenaga, Tsuyoshi Mutou, Junko Hirano, Akira Sakakura, Takeshi Ogawa, Masanori Nisiwaki, Kiyoyuki Yamada,* Tetrahedron Lett. 1994, 35, 1247–1250.
DOI: 10.1016/0040-4039(94)88035-2
2. "Total Synthesis of Aplyronine A, a Potent Antitumor Substance of Marine Origin"
Hideo Kigoshi, Makoto Ojika, Takeshi Ishigaki, Kiyotake Suenaga, Tsuyoshi Mutou, Akira Sakakura, Takeshi Ogawa, Kiyoyuki Yamada,* J. Am. Chem. Soc. 1994, 116, 7443–7444.
DOI: 10.1021/ja00095a072
3. "Absolute Stereochemistry and Synthesis of Aplyronines B and C, the Congeners of Aplyronine A, a Potent Antitumor Substance of Marine Origin"
Kiyotake Suenaga, Takeshi Ishigaki, Akira Sakakura, Hideo Kigoshi, Kiyoyuki Yamada,* Tetrahedron Lett. 1995, 36, 5053–5056.
DOI: 10.1016/0040-4039(95)00921-X
4. "Aplyronine A, a Potent Antitumor Substance of Marine Origin, Aplyronines B and C, and Artificial Analogues: Total Synthesis and Structure–Cytotoxicity Relationships"
Hideo Kigoshi, Kiyotake Suenaga, Tsuyoshi Mutou, Takeshi Ishigaki, Toshiyuki Atsumi, Hiroyuki Ishiwata, Akira Sakakura, Takeshi Ogawa, Makoto Ojika, Kiyoyuki Yamada,* J. Org. Chem. 1996, 61, 5326–5351.
DOI: 10.1021/jo9606113
5. "A Novel Approach to Oligodeoxyribonucleotides Bearing Phosphoric Acid Esters at the 3’-Terminals via the Phosphoramidite Method with Allyl Protection: an Efficient Synthesis of Base-Labile Nucleotide–Amino Acid and –Peptide Conjugates"
Akira Sakakura, Yoshihiro Hayakawa,* Hitoshi Harada, Masaaki Hirose, Ryoji Noyori,* Tetrahedron Lett. 1999, 40, 4359–4362.
DOI: 10.1016/S0040-4039(99)00748-0
6. "A Novel Synthesis of Oligonucleotide–Peptide Conjugates with a Base-Labile Phosphate Linker between the Two Components According to the Allyl-Protected Phosphoramidite Strategy"
Akira Sakakura, Yoshihiro Hayakawa,* Tetrahedron 2000, 56, 4427–4435.
DOI: 10.1016/S0040-4020(00)00376-8
7. "A Facile Synthesis of 5’-End Solid-Anchored, 3’-End Free Oligodeoxyribonucleotides via the (5’→3’)-Elongated Phosphoramidite Strategy"
Akira Sakakura, Yoshihiro Hayakawa,* Nucleosides, Nucleotides, Nucleic Acids 2001, 20, 213–227.
DOI: 10.1081/NCN-100002082
8. "Acid/Azole Complexes as Highly Effective Promoters in the Synthesis of DNA and RNA Oligomers via the Phosphoramidite Method"
Yoshihiro Hayakawa,* Rie Kawai, Akiyoshi Hirata, Jun-ichiro Sugimoto, Masanori Kataoka, Akira Sakakura, Masaaki Hirose, and Ryoji Noyori, J. Am. Chem. Soc. 2001, 123, 8165–8176.
DOI: 10.1021/ja010078v
9. "Effect of Molecular Sieves in the Liquid-Phase Synthesis of Nucleotides via the Phosphoramidite Method"
Yoshihiro Hayakawa,* Akiyoshi Hirata, Jun-ichiro Sugimoto, Rie Kawai, Akira Sakakura, Masanori Kataoka, Tetrahedron 2001, 57, 8823–8826.
DOI: 10.1016/S0040-4020(01)00880-8
10. "Jolkinolide D Pharmacophore: Synthesis and Reaction with Amino Acids, Nucleosides, and DNA"
Akira Sakakura, Yui Takayanagi, Hideo Kigoshi,* Tetrahedron Lett. 2002, 43, 6055–6058.
DOI: 10.1016/S0040-4039(02)01195-4
11. "Nonspecificity Induces Chiral Specificity in the Folding Transition of Giant DNA"
Michiko Ito, Akira Sakakura, Naomi Miyazawa, Shizuaki Murata,* Kenichi Yoshikawa, J. Am. Chem. Soc. 2003, 125, 12714–12715.
DOI: 10.1021/ja036745x
12. "Jolkinolide D Pharmacophore: Synthesis and Reaction with Biomolecules"
Akira Sakakura, Yui Takayanagi, Hiroki Shimogawa, Hideo Kigoshi,* Tetrahedron 2004, 60, 7067–7075.
DOI: 10.1016/j.tet.2003.08.080
13. "Synthesis and actin-depolymerizing activity of mycalolide analogs"
Kiyotake Suenaga, Saori Miya, Takeshi Kuroda, Tomohisa Handa, Kengo Kanematsu, Akira Sakakura, Hideo Kigoshi,* Tetrahedron Lett. 2004, 45, 5383–5386.
DOI: 10.1016/j.tetlet.2004.05.078
14. "Spongiacysteine, a Novel Cysteine Derivative from Marine Sponge Spingia sp."
Keiko Kobayashi, Hiroki Shimogawa, Akira Sakakura, Toshiaki Teruya, Kiyotake Suenaga, Hideo Kigoshi,* Chem. Lett. 2004, 33, 1262–1263.
DOI: 10.1246/cl.2004.1262
15. "Formal Synthesis of Optically Active Ingenol via Ring-Closing Olefin Methathesis"
Kazushi Watanabe, Yuto Suzuki, Kenta Aoki, Akira Sakakura, Kiyotake Suenaga, Hideo Kigoshi,* J. Org. Chem. 2004, 69, 7802–7808.
DOI: 10.1021/jo048833l
16. "Bulky Diarylammonium Arenesulfonates as Selective Esterification Catalysts"
Kazuaki Ishihara,* Shoko Nakagawa, Akira Sakakura, J. Am. Chem. Soc. 2005, 127, 4168–4169.
DOI: 10.1021/ja050223v
17. "Molybdenum Oxides as Highly Effective Dehydrative Cyclization Catalysts for the Synthesis of Oxazolines and Thiazolines"
Akira Sakakura, Rei Kondo, Kazuaki Ishihara,* Org. Lett. 2005, 7, 1971–1974.
DOI: 10.1021/ol050543j
18. "Selective Synthesis of Phosphate Monoesters by Dehydrative Condensation of Phosphoric Acid and Alcohols Promoted by Nucleophilic Bases"
Akira Sakakura, Mikimoto Katsukawa, Kazuaki Ishihara,* Org. Lett. 2005, 7, 1999–2002.
DOI: 10.1021/ol0504796
19. "Bulky diarylammonium arenesulfonates as mild and extremely active dehydrative ester condensation catalysts"
Akira Sakakura, Shoko Nakagawa, Kazuaki Ishihara,* Tetrahedron 2006, 62, 422–433.
DOI: 10.1016/j.tet.2005.09.059
20. "Study of the Interaction between Actin and Antitumor Substance Aplyronine A with a Novel Fluorescent Photoaffinity Probe"
Takeshi Kuroda, Kiyotake Suenaga, Akira Sakakura, Tomohisa Handa, Kazuhito Okamoto, Hideo Kigoshi,* Bioconjugate Chem. 2006, 17, 524–529.
DOI: 10.1021/bc050324i
21. "Chiral 1,1'-Binaphthyl-2,2'-diammonium Salt Catalysts for the Enantioselective Diels–Alder Reaction with α-Acyloxyacroleins"
Akira Sakakura, Kenji Suzuki, Kazuhiko Nakano, Kazuaki Ishihara,* Org. Lett. 2006, 8, 2229−2232.
DOI: 10.1021/ol060490l
22. "Enantioselective Diels–Alder Reaction of α-Acyloxyacroleins Catalyzed by Chiral 1,1'-Binaphthyl-2,2'-diammonium Salts"
Akira Sakakura, Kenji Suzuki, Kazuaki Ishihara,* Adv. Synth. Catal. 2006, 348, 2457–2465.
DOI: 10.1002/adsc.200600322
23. "Enantioselective synthesis of aurisides A and B, cytotoxic macrolide glycosides of marine origin"
Kiyotake Suenaga, Hiroshi Hoshino, Takanori Yoshii, Kazunori Mori, Hiroki Sone, Yuhki Bessho, Akira Sakakura, Ichiro Hayakawa, Kiyoyuki Yamada, Hideo Kigoshi,* Tetrahedron 2006, 62, 7687–7698.
DOI: 10.1016/j.tet.2006.05.077
24. "Synthesis and biological activity of mycalolide analogs"
Kiyotake Suenaga,* Tomoyuki Kimura, Takeshi Kuroda, Keita Matsui, Saori Miya, Satomi Kuribayashi, Akira Sakakura, Hideo Kigoshi,* Tetrahedron2006, 62, 8278–8290.
DOI: 10.1016/j.tet.2006.06.046
25. "The Oxorhenium(VII)-Catalyzed Direct Condensation of Phosphoric Acid with an Alcohol"
Akira Sakakura, Mikimoto Katsukawa, Kazuaki Ishihara,* Angew. Chem. Int. Ed. 2007, 46, 1423–1426.
DOI: 10.1002/anie.200604333
26. "Enantioselective halocyclization of polyprenoids induced by nucleophilic phosphoramidites"
Akira Sakakura, Atsushi Ukai, Kazuaki Ishihara,* Nature 2007, 455, 900–903.
DOI: 10.1038/nature05553
27. "Dehydrative Cyclization Catalyzed by the Combination of Molybdenum(VI) Oxides and Benzoic Acids: First Synthesis of the Antitumor Substance BE-70016"
Akira Sakakura, Shuhei Umemura, Rei Kondo, Kazuaki Ishihara,* Adv. Synth. Catal. 2007, 349, 551–555.
DOI: 10.1002/adsc.200600550
28. "Unusual Rate-Acceleration in the Brønsted Acid-Catalyzed Dehydration Reactions: Local Hydrophobic Environment in Aggregated N-(2,6-Diphenylphenyl)-N-mesitylammonium Pentafluorobenzenesulfonates"
Akira Sakakura, Hitoshi Watanabe, Shoko Nakagawa, Kazuaki Ishihara,* Chem. Asian J. 2007, 2, 477–483.
DOI: 10.1002/asia.200600380
29. "Catalytic Synthesis of Peptide-Derived Thiazolines and Oxazolines Using Bis(quinolinolato)dioxomolybdenum(VI) Complexes"
Akira Sakakura, Rei Kondo, Shuhei Umemura, Kazuaki Ishihara,* Adv. Synth. Catal. 2007, 349, 1641–1646.
DOI: 10.1002/adsc.200700068
30. "Direct ester condensation catalyzed by bulky diarylammonium pentafluorobenzenesulfonates"
Akira Sakakura, Shoko Nakagawa, Kazuaki Ishihara,* Nature Protocols 2007, 2, 1746–1751.
DOI: 10.1038/nprot.2007.254
31. "Bulky phosphazenium cation catalysis for dehydrative condensation of phosphoric acid with alcohols"
Akira Sakakura, Mikimoto Katsukawa, Takaomi Hayashi, Kazuaki Ishihara,* Green Chem. 2007, 9, 1166–1169.
DOI: 10.1039/B707974E
32. "Widely Useful DMAP-Catalyzed Esterification under Auxiliary Base- and Solvent-Free Conditions"
Akira Sakakura, Kimio Kawajiri, Takuro Ohkubo, Yuji Kosugi, Kazuaki Ishihara,* J. Am. Chem. Soc. 2007, 129, 14775–14779.
DOI: 10.1021/ja075824w
33. "Selective Synthesis of Cyclic Phosphoric Acid Diesters Through Oxorhenium(VII)-Catalyzed Dehydrative Condensation of Phosphoric Acid with Alcohols"
Akira Sakakura, Masayuki Sakuma, Mikimoto Katsukawa, Kazuaki Ishihara,* Heterocycles 2008, 76, 657–665.
DOI: 10.3987/COM-08-S(N)58
34. "Convergent Total Syntheses of Fluvibactin and Vibriobactin Using Molybdenum(VI) Oxide-Catalyzed Dehydrative Cyclization as a Key Step"
Akira Sakakura, Shuhei Umemura, Kazuaki Ishihara,* Chem. Commun. 2008, 3561–3563.
DOI: 10.1039/B805880F
35. "Rate-Accelerating Effect by the Neighboring-Group Participation of Protecting Groups in the Dehydrative Cyclization of 1,3,5-Triketones"
Akira Sakakura, Hitoshi Watanabe, Kazuaki Ishihara,* Org. Lett. 2008, 10, 2569–2572.
DOI: 10.1021/ol800860p
36. "Kinetic Resolution of Racemic Carboxylic Acids by an L-Histidine-derived Sulfonamide-induced Enantioselective Esterification Reaction"
Kazuaki Ishihara,* Yuji Kosugi, Shuhei Umemura, Akira Sakakura, Org. Lett. 2008, 10, 3191–3194.
DOI: 10.1021/ol801007m
37. "Open-air and solvent-free ester condensation catalyzed by sulfuric acids"
Akira Sakakura, Yoshiki Koshikari, Kazuaki Ishihara,* Tetrahedron Lett. 2008, 49, 5017–5020.
DOI: 10.1016/j.tetlet.2008.06.058
38. "Dehydrative cyclization of serine, threonine and cysteine residues catalyzed by molybdenum(VI) oxo compounds"
Akira Sakakura, Rei Kondo, Shuhei Umemura, Kazuaki Ishihara,* Tetrahderon 2009, 65, 2102–2109.
DOI: 10.1016/j.tet.2008.12.074
39. "3-Pyrroline-1-carbonyl (Pyroc) Group: A Removable Protecting Group for the Kinetic Resolution of Racemic Carboxylic Acids and Alcohols through Catalytic Asymmetric Acylation"
Akira Sakakura, Shuhei Umemura, Kazuaki Ishihara,* Synlett 2009, 1647–1650.
DOI: 10.1055/s-0029-1217321
40. "Rational Design of Highly Effective Asymmetric Diels-Alder Catalysts Bearing 4,4′-Sulfonamidomethyl Groups"
Akira Sakakura, Rei Kondo, Yuki Matsumura, Matsujiro Akakura, Kazuaki Ishihara,* J. Am. Chem. Soc. 2009, 131, 17762–17764.
DOI: 10.1021/ja906098b
41. "Nucleophilic Phosphine–Catalyzed Iodocyclization of Isoprenoids Bearing an Oxygen Terminal Group"
Akira Sakakura, Gakujun Shomi, Atsushi Ukai, Kazuaki Ishihara,* Heterocycles 2010, 82, 249–255.
DOI: 10.3987/COM-09-S(E)1
42. "Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Nitrones with Propioloylpyrazoles and Acryloylpyrazoles Induced by Chiral π–Cation Catalysts"
Akira Sakakura, Masahiro Hori, Makoto Fushimi, Kazuaki Ishihara,* J. Am. Chem. Soc. 2010, 132, 15550–15552.
DOI: 10.1021/ja1081603
43. "Brønsted Base-Assisted Boronic Acid Catalysis for the Dehydrative Intramolecular Condensation of Dicarboxylic Acids"
Akira Sakakura, Takuro Ohkubo, Risa Yamashita, Matsujiro Akakura, Kazuaki Ishihara,* Org. Lett. 2011, 13, 892–895.
DOI: 10.1021/ol102926n
44. "Chiral Lewis Base-Assisted Brønsted Acid (LBBA)-Catalyzed Enantioselective Cyclization of 2-Geranylphenols"
Akira Sakakura, Masayuki Sakuma, Kazuaki Ishihara,* Org. Lett. 2011, 13, 3130–3133.
DOI: 10.1021/ol201032t
45. "Desymmetrization of Meso Glycerol Derivatives Induced by L-Histidine-Derived Acylation Catalysts"
Akira Sakakura, Shuhei Umemura, Kazuaki Ishihara,* Adv. Synth. Catal. 2011, 353, 1938–1942.
DOI: 10.1002/adsc.201100252
46. "Intramolecular Dehydrative Condensation of Dicarboxylic Acids with Brønsted Base-Assisted Boronic Acid Catalysts"
Akira Sakakura, Risa Yamashita, Takuro Ohkubo, Matsujiro Akakura, Kazuaki Ishihara,* Aust. J. Chem. 2011, 64, 1458–1465.
DOI: 10.1071/CH11301
47. "Hydrophobic N,N-Diarylammonium Pyrosulfates as Dehydrative Condensation Catalysts under Aqueous Conditions"
Akira Sakakura, Yoshiki Koshikari, Matsujiro Akakura, Kazuaki Ishihara,* Org. Lett. 2012, 14, 30–33.
DOI: 10.1021/ol2027366
48. "Aplyronines D–H from the sea hare Aplysia kurodai: isolation, structures, and cytotoxicity"
Makoto Ojika,* Hideo Kigoshi, Kiyotake Suenaga, Yoshifumi Imamura, Kohji Yoshikawa, Takeshi Ishigaki, Akira Sakakura, Tsuyoshi Mutou, Kiyoyuki Yamada,* Tetrahedron 2012, 68, 982–987.
DOI: 10.1016/j.tet.2011.11.095
49. "Enantioselective Diels–Alder Reaction of α-(Acylthio)acroleins: a New Entry to Sulfur-containing Chiral Quaternary Carbons"
Akira Sakakura, Hiroki Yamada, Kazuaki Ishihara,* Org. Lett. 2012, 14, 2972–2975.
DOI: 10.1021/ol300921f
50. "N,N-Diarylammonium Pyrosulfate as a Highly Effective Reverse Micelle-type Catalyst for Hydrolysis of Esters"
Yoshiki Koshikari, Akira Sakakura, Kazuaki Ishihara,* Org. Lett. 2012, 14, 3194–3197.
DOI: 10.1021/ol301290c
51. "α-Heterosubstituted β-Alkylacroleins as Useful Multisubstituted Dienophiles for Enantioselective Diels-Alder Reactions"
Akira Sakakura, Hiroki Yamada, Kazuaki Ishihara,* Asian J. Org. Chem. 2012, 1, 133–137.
DOI: 10.1002/ajoc.201200054
52. "Kinetic Resolution of Racemic Carboxylic Acids through Asymmetric Protolactonization Promoted by Chiral Phosphonous Acid Diester"
Masayuki Sakuma, Akira Sakakura,* Kazuaki Ishihara,* Org. Lett. 2013, 15, 2838–2841.
DOI: 10.1021/ol401313d
53. "Primary Alkylboronic Acids as Highly Active Catalysts for the Dehydrative Amide Condensation of α-Hydroxycarboxylic Acids"
Risa Yamashita, Akira Sakakura,* Kazuaki Ishihara,* Org. Lett. 2013, 15, 3654–3657.
DOI: 10.1021/ol401537f
54. "Enantioselective Cyanoethoxycarbonylation of Isatins Promoted by a Lewis Base–Brønsted Acid Cooperative Catalyst"
Yoshihiro Ogura, Matsujiro Akakura, Akira Sakakura,* Kazuaki Ishihara,* Angew. Chem. Int. Ed. 2013, 52, 8299–8303.
DOI: 10.1002/anie.201303572
55. "“Phosphite–Urea” Cooperative High-Turnover Catalysts for the Highly Selective Bromocyclization of Homogeranylarenes"
Yasuhiro Sawamura, Hidefumi Nakatsuji, Akira Sakakura,* Kazuaki Ishihara,* Chem. Sci. 2013, 4, 4181–4186.
DOI: 10.1039/C3SC51432C
56. "Selective Bromocyclization of 2-Geranylphenols Promoted by Phosphite–Urea Cooperative Catalysts"
Yasuhiro Sawamura, Hidefumi Nakatsuji, Matsujiro Akakura, Akira Sakakura,* Kazuaki Ishihara,* Chirality 2014, 26, 356–360.
DOI: 10.1002/chir.22297
57. "Catalytic Enantioselective Inverse Electron Demand Hetero-Diels–Alder Reaction with Allylsilanes"
Yuki Matsumura, Takahiro Suzuki, Akira Sakakura,* Kazuaki Ishihara,* Angew. Chem. Int. Ed. 2014, 53, 6131–6134.
DOI: 10.1002/anie.201402934
58. "Cooperative Activation with Chiral Nucleophilic Catalysts and N-Haloimides: Enantioselective Iodolactonization of 4-Arylmethyl-4-pentenoic Acids"
Hidefumi Nakatsuji, Yasuhiro Sawamura, Akira Sakakura,* Kazuaki Ishihara,* Angew. Chem. Int. Ed. 2014, 53, 6974–6977.
DOI: 10.1002/anie.201400946
59. "Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Imines with Propioloylpyrazoles Induced by Chiral π−Cation Catalysts"
Masahiro Hori, Akira Sakakura,* Kazuaki Ishihara,* J. Am. Chem. Soc. 2014, 136, 13198–13201.
DOI: 10.1021/ja508441t
60. "Stereoselective Electrophilic Cyclization"
Akira Sakakura,* Kazuaki Ishihara,* Chem. Rec. 2015, 15, 728–742.
DOI: 10.1002/tcr.201500005
61. "Enantioselective Bromocyclization of 2-Gernaylphenols Induced by Chiral Phosphite-Urea Bifunctional Catalysts"
Yasuhiro Sawamura, Yoshihiro Ogura, Hidefumi Nakatsuji, Akira Sakakura,* Kazuaki Ishihara,* Chem. Common. 2016, 52, 6068–6071.
DOI: 10.1039/C6CC00229C
62. "A short access to 3,5-disubstituted piperazinones based on the aza-Michael addition of α-amino esters to β-substituted nitroalkenes"
Takayuki Kudoh,* Seiji Isoyama, Sachiko Kagimoto, Katsutoshi Kurihara, Akira Sakakura,* Tetrahedron Lett. 2016, 57, 4693–4696.
DOI: 10.1016/j.tetlet.2016.09.015
63. "Discovery of O6-benzyl glaziovianin A, a potent cytotoxic substance and a potent inhibitor of α,β-tubulin polymerization"
Ichiro Hayakawa,* Shuya Shioda, Takumi Chinen, Taisei Hatanaka, Haruna Ebisu, Akira Sakakura, Takeo Usui,* Hideo Kigoshi,* Bioorg. Med. Chem.2016, 24, 5639–5645.
DOI: 10.1016/j.bmc.2016.09.026
64. "Reinvestigation of the Biomimetic Cyclization of 3,5-Diketo Esters: Application to the Total Synthesis of Cyercene A, an α-Methoxy-γ-Pyrone-Containing Polypropionate"
Kai Onda, Ichiro Hayakawa, Akira Sakakura,* Synlett 2017, 28, 1596–1600.
DOI: 10.1055/s-0036-1588795
65. "Heat Versus Basic Conditions: Intramolecular Dehydro-Diels–Alder Reaction of 1-Indolyl-1,6-heptadiynes for the Selective Synthesis of Substituted Carbazoles"
Takayuki Kudoh, Syo Fujisawa, Megumi Kitamura, Akira Sakakura,* Synlett 2017, 28, 2189–2193.
DOI: 10.1055/s-0036-1588461
66. "Diastereodivergent Henry Reaction for the Stereoselective Construction of Nitrogen-Containing Tetrasubstituted Carbons: Application to Total Synthesis of Manzacidins A and C"
Takayuki Kudoh, Yuya Araki, Natsumi Miyoshi, Mizuho Tanioka, Akira Sakakura,* Asian J. Org. Chem. 2017, 6, 1760–1763.
DOI: 10.1002/ajoc.201700568
67. "Regioselective DMAD-insertion reaction of silyl dienol ether of γ-pyrone under catalyst- and heating-free conditions"
Ichiro Hayakawa,* Yuji Yamanaka, Koichi Mitsudo, Hiromi Ota, Akira Sakakura,* Heterocycles 2017, 94, 2299–2306.
DOI: 10.3987/COM-17-13820
68. "Enantioselective Aza-Friedel–Crafts Reaction of Furan with α-Ketimino Esters Induced by a Conjugated Double Hydrogen Bond Network of Chiral Bis(phosphoric Acid) Catalysts"
Manabu Hatano, Haruka Okamoto, Taro Kawakami, Kohei Toh, Hidefumi Nakatsuji, Akira Sakakura,* Kazuaki Ishihara,* Chem. Sci. 2018, 9 (30), 6361–6367.
DOI: 10.1039/C8SC02290A
69. "Chiral Pyrophosphoric Acid Catalysts for the para-Selective and Eanantioselective Aza-Friedel–Crafts Reaction of Phenols"
Haruka Okamoto, Kohei Toh, Takuya Mochizuki, Hidefumi Nakatsuji, Akira Sakakura,* Manabu Hatano,* Kazuaki Ishihara,* Synthesis 2018, 50 (23), 4577–4590.
DOI: 10.1055/s-0037-1610250
70. "Catalytic Enantioselective Hosomi–Sakurai Reaction of α-Ketoesters Promoted by Chiral Copper(II) Complexes"
Yutaro Niwa, Mayu Miyake, Ichiro Hayakawa, Akira Sakakura,* Chem. Commun. 2019, 55 (27), 3923–3926.
DOI: 10.1039/C9CC01159E
71. "Thioureas as Highly Active Catalysts for Biomimetic Bromocyclization of Geranyl Derivatives"
Miyuki Terazaki, Kei-ichi Shiomoto, Haruki Mizoguchi, Akira Sakakura,* Org. Lett. 2019, 21 (7), 2073–2076.
DOI: 10.1021/acs.orglett.9b00352
72. "Enantioselective 1,3-Dipolar Cycloaddition Reaction of Nitrones with α-(Acyloxy)acroleins Catalyzed by Dipeptide-Derived Chiral Tri- or Diammonium Salts"
Chihiro Kidou, Haruki Mizoguchi, Tatsuo Nehira, Akira Sakakura,* Synlett 2019, 30 (15), 1835–1839.
DOI: 10.1055/s-0039-1690133
73. "Toward the Synthesis of Yuzurimine-type Alkaloids: Stereoselective Construction of the Heterocyclic Portions of Deoxyyuzurimine and Macrodaphnine"
Ichiro Hayakawa,* Ryosuke Nagatani, Masaki Ikeda, Dong-eun Yoo, Keita Saito, Hideo Kigoshi, Akira Sakakura,* Org. Lett. 2019, 21 (16), 6337–6341.
DOI: 10.1021/acs.orglett.9b02232
74. "Toward the Synthesis of SB-203207: Construction of Four Contiguous Nitrogen-Containing Stereogenic Centers"
Ichiro Hayakawa,* Anna Nagayasu, Akira Sakakura,* J. Org. Chem. 2019, 84 (23), 15614–15623.
DOI: 10.1021/acs.joc.9b02627
75. "Formal Total Synthesis of Manzacidin B via Sequential Diastereodivergent Henry Reaction"
Yuya Araki, Natsumi Miyoshi, Kazuki Morimoto, Takayuki Kudoh, Haruki Mizoguchi, Akira Sakakura,* J. Org. Chem. 2020, 85 (2), 798–805.
DOI: 10.1021/acs.joc.9b02811
76. "Structure Optimization of Gatastatin for the Development of γ-Tubulin-Specific Inhibitor"
Kana Shintani, Haruna Ebisu, Minagi Mukaiyama, Taisei Hatanaka, Takumi Chinen, Daisuke Takao, Yoko Nagumo, Akira Sakakura, Ichiro Hayakawa,* Takeo Usui,* ACS Med. Chem. Lett. 2020, 11 (6), 1125–1129.
DOI: 10.1021/acsmedchemlett.9b00526
77. "Enantioselective Diels–Alder Reaction of 3-Nitrocoumarins Promoted by Chiral Organoammonium Salt Catalysts"
Yudai Fujii, Ryota Nakao, Saki Sugihara, Keita Fujita, Yuya Araki, Takayuki Kudoh, Ichiro Hayakawa, Haruki Mizoguchi, Akira Sakakura,* Synlett 2020, 31 (20), 2013–2017.
DOI: 10.1055/s-0040-1707302
78. "Kinetic Resolution of α-Nitrolactones by Catalytic Asymmetric Hydrolysis or Ester–Amide Exchange Reaction"
Ryota Nakao, Yudai Fujii, Ichiro Hayakawa, Haruki Mizoguchi, Akira Sakakura,* Synlett 2020, 31 (20), 2018–2022.
DOI: 10.1055/s-0040-1707303
79. "Synthesis of functionalized cyclopropylboronic esters based on a 1,2-metallate rearrangement of cyclopropenylboronate"
Haruki Mizoguchi,* Masaya Seriua, Akira Sakakura,* Chem. Commun. 2020, 56 (99), 15545–15548.
DOI: 10.1039/d0cc07134j
80. "Toward the Synthesis of Paspaline-Type Indole-Terpenes: Stereoselective Construction of Core Scaffold with Contiguous Asymmetric Quaternary Carbon Centers"
Ichiro Hayakawa*, Naochika Matsumaru, and Akira Sakakura,* J. Org. Chem. 2021, ASAP
DOI: 10.1021/acs.joc.1c01193
解説，総説など
1.「第２章 フルオラスケミストリーの基礎」
John A. Gladysz（翻訳：坂倉彰，石原一彰）
フルオラスケミストリー，監修：大寺純蔵，シーエムシー出版, 2005, pp. 161–169.
2.「プロスタグランジンの鍵中間体の画期的合成法」
坂倉彰
化学，注目の論文，化学同人，2006, 61, 64–65.
3. 「環境低負荷型触媒的脱水反応プロセスの開発」
坂倉彰，石原一彰
有機合成化学協会誌, 2006, 64, 651–663.
"Development of environmentally benign catalytic dehydration process"
Akira Sakakura, Kazuaki Ishihara
Journal of Synthetic Organic Chemistry Japan 2006, 64, 651–663.
4. "Design of Highly Functional Small-Molecule Catalysts and Related Reactions Based on Acid–Base Combination Chemistry"
Kazuaki Ishihara, Akira Sakakura, Manabu Hatano
Synlett 2007, 686–703.
DOI: 10.1055/s-2007-970776
5.「Simple is bestで掴んだ思わぬ大発見！—無塩基・無溶媒条件でのDMAP触媒エステル合成法」
坂倉彰，石原一彰
化学，研究物語，2007, 63, 12–16.
6. "Enantioselective biomimetic polyene cyclization of polyprenoids"
Akira Sakakura, Kazuaki Ishihara
Chimica Oggi-Chemistry Today (Suppl. Chiral Technologies) 2007, 25, 9–12.
7. 「酸・塩基複合塩を鍵とする高機能触媒の設計および高選択的合成法の開拓」
坂倉彰
有機合成化学協会誌, 2008, 66, 942–952.
"Design of High-Performance Catalysts Based on Acid–Base Combined Salts and Development of Highly Selective Reactions"
Akira Sakakura
Journal of Synthetic Organic Chemistry Japan 2008, 66, 942–952.
8.「第11章 酸塩基複合触媒 付加環化反応を中心として」
坂倉彰，石原一彰
進化を続ける有機触媒 有機合成を革新する第三の触媒，編集：丸岡啓二，化学同人，2009, pp. 128–135.
9. "Organoammonium Salt-Catalyzed Enantioselective Cycloaddition Reactions with α-(Acyloxy)- or α-Diacylaminoacroleins"
Akira Sakakura, Kazuaki Ishihara
Bull. Chem. Soc. Jpn 2010, 83, 313–322.
DOI: 10.1246/bcsj.20090345
10.「弱い二次的相互作用を鍵とする不斉触媒の精密設計—ルイス塩基によるルイス酸触媒の活性化と柔軟な不斉反応場の構築」
坂倉彰
化学と工業，支部発話題欄，2010, (3), 238–239.
11. "Asymmetric Cu(II) catalyses for cycloaddition reactions based on π–cation or n–cation interaction"
Akira Sakakura, Kazuaki Ishihara
Chem. Soc. Rev. 2011, 40, 163–172.
DOI: 10.1039/B924478F
12. “3.2 [4+2]-Cycloaddition Reactions”
Kazuaki Ishihara, Akira Sakakura
In Science of Synthesis, Stereoselective Synthesis 3: Stereoselective Pericyclic Reactions, Cross Coupling, and C–H and C–X Activation;
Evans, P. A., Ed., Georg Thieme Verlag: Stuttgart, 2011, pp. 67–123.
13. “7.10 C–C bond formation | Diels–Alder reaction”
Kazuaki Ishihara, Akira Sakakura
In Comprehensive Chirality: Synthetic Methods V – Organocatalysis; Hisashi Yamamoto and Eric Carreira, Eds., Elsevier: Oxford, 2012, pp. 264–292.
DOI: 10.1016/B978-0-08-095167-6.00610-8
14. "5.9 Intermolecular Diels–Alder Reactions"
Kazuaki Ishihaira, Akira Sakakura
In Comprehensive Organic Synthesis, 2nd Edition, Vol. 5, Gary A. Molander and Paul Knochel (eds.), Oxford: Elsevier; 2014, pp. 351-408.
15. "5.10 Hetero-Diels–Alder Reactions"
Kazuaki Ishihaira, Akira Sakakura
In Comprehensive Organic Synthesis, 2nd Edition, Vol. 5, Gary A. Molander and Paul Knochel (eds.), Oxford: Elsevier; 2014, pp. 409-465.
16. “Copper(II) Triflimide”
Akira Sakakura, Kazuaki Ishihara
In e-EROS (Encyclopedia of Reagents for Organic Synthesis); Wiley, 2017, Chapter April 2017, pp. 1–4.
DOI: 10.1002/047084289X.rn01746
First published : 10 April 2017
17. 「チタンを用いるクロスカップリング－ステロイドやテルペノイド合成への新たなアプローチ」
溝口玄樹，坂倉彰
化学，最新のトピックス，化学同人，2018, 73, 68–69.
18. "Strain-Release Difunctionalization of C–C σ- and π-bonds of an Organoboron Ate-Complex through 1,2-Metallate Rearrangement"
Haruki Mizoguchi,* Akira Sakakura,* Chem. Lett. 2021, 50 (4), 792–799.
DOI: 10.1246/cl.200926